Clinical Trial Highlights:

In the SURMOUNT trials, patients achieved an average of 20.9% weight loss at the highest dose - results that exceeded all expectations and set new standards in weight management therapy.

Mechanism of Action

  • GLP-1 Receptor Activation: Stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, and slows gastric emptying

  • GIP Receptor Activation: Enhances insulin sensitivity and may have direct effects on fat metabolism

  • Appetite Regulation: Acts on brain receptors to reduce appetite and food intake

  • Gastric Motility: Slows gastric emptying, leading to increased satiety

Transformative Results

Diabetes Management:

  • Significant reduction in HbA1c levels.

  • Improved glycemic control

  • Low risk of hypoglycemia

  • Cardiovascular benefits

Weight Management Success:

  • Average weight loss of 15-22% in clinical trials

  • Sustained weight reduction

  • Improved body composition

  • Reduction in waist circumference